The single goal of the spermatozoon is to deliver the paternal counterpart of genetic material to the oocyte.
When one refers to the sperm as a whole functional cell, it is not just for its role as a carrier but for its contents as well.
Subfertility affects between 15% – 25% of couples. Approximately 20% of infertile couples, the male partner is the sole cause. Male infertility can be due to a variety of conditions.
DNA integrity was recognized as a significant sperm functional parameter with an important role in human ART.
That unique chromatin structure protects father’s genome from external influences enabling its correct transfer towards oocyte.
The DNA integrity is the sperm functional parameter that together with conventional semen parameters gives more reliable and precise diagnosis of male reproductive potential.
With the Sperm DNA fragmentation assay kit from the range of halo around the head of sperm highly contrasted and halo images can be accurately assessed using
conventional bright-field microscopy after staining.
Sperm tails are preserved, making it possible to unequivocally discriminate sperm from other cell types and also to identify degraded sperm cells beside the one with big, medium or no halo.
Sperm DNA integrity balanced with other semen parameters provides clinicians with important information to help select the most appropriate therapy for the couple.
Sperm DNA fragmentation can often be improved, typically with simple lifestyle changes, such as quitting smoking, decreasing excess body weight, or having
more frequent intercourse.
Testing sperm DNA fragmentation proactively allows couples to address and resolve issues on their own, potentially saving time, money, and energy all of which are often in short supply for fertility patients as well as improving outcomes for both the parents and the child.
Sperm sample
Fresh semen samples should be collected in a sterile container. The sperm DNA fragmentation assay should be performed. fresh semen is needed.
Store condition
After receiving the SDFA kit store at 2-8 º for 8 months.
INSTRUCTION FOR USE
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